Transcriptomic profiling of human hippocampal progenitor cells treated with antidepressants and its application in drug repositioning

Current pharmacological treatments for major depressive disorder (MDD) are ineffective in a significant proportion of patients, and the identification of new antidepressant compounds has been difficult. ‘Connectivity mapping’ is a method that can be used to identify drugs that elicit similar downstr...

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Bibliografiske detaljer
Udgivet i:J Psychopharmacol
Main Authors: Powell, Timothy R, Murphy, Tytus, Lee, Sang H, Price, Jack, Thuret, Sandrine, Breen, Gerome
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2017
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Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349314/
https://ncbi.nlm.nih.gov/pubmed/28208023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0269881117691467
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