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The transcriptional repressor Sum1p counteracts Sir2p in regulation of the actin cytoskeleton, mitochondrial quality control and replicative lifespan in Saccharomyces cerevisiae

Increasing the stability or dynamics of the actin cytoskeleton can extend lifespan in C. elegans and S. cerevisiae. Actin cables of budding yeast, bundles of actin filaments that mediate cargo transport, affect lifespan control through effects on mitochondrial quality control. Sir2p, the founding me...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Higuchi-Sanabria, Ryo, Vevea, Jason D., Charalel, Joseph K., Sapar, Maria L., Pon, Liza A.
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5349106/
https://ncbi.nlm.nih.gov/pubmed/28357337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2016.02.478
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