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Deletion of AIF1 but not of YCA1/MCA1 protects Saccharomyces cerevisiae and Candida albicans cells from caspofungin-induced programmed cell death

Caspofungin was the first member of a new class of antifungals called echinocandins to be approved by a drug regulatory authority. Like the other echinocandins, caspofungin blocks the synthesis of β(1,3)-D-glucan of the fungal cell wall by inhibiting the enzyme, β(1,3)-D-glucan synthase. Loss of β(1...

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Detalhes bibliográficos
Publicado no:Microb Cell
Main Authors: Chin, Christopher, Donaghey, Faith, Helming, Katherine, McCarthy, Morgan, Rogers, Stephen, Austriaco, Nicanor
Formato: Artigo
Idioma:Inglês
Publicado em: Shared Science Publishers OG 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348969/
https://ncbi.nlm.nih.gov/pubmed/28357223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15698/mic2014.01.119
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