Effect of Moringa oleifera Lam. leaf powder on the pharmacokinetics of nevirapine in HIV-infected adults: a one sequence cross-over study

BACKGROUND: Moringa oleifera Lam., an herb commonly consumed by HIV-infected people on antiretroviral therapy, inhibits cytochrome P450 3A4, 1A2 and 2D6 activity in vitro; and may alter the pharmacokinetics (PK) of antiretroviral drugs metabolized via the same pathways. However, in vitro drug intera...

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Publicat a:AIDS Res Ther
Autors principals: Monera-Penduka, Tsitsi G., Maponga, Charles C., Wolfe, Alan R., Wiesner, Lubbe, Morse, Gene D., Nhachi, Charles F. B.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348890/
https://ncbi.nlm.nih.gov/pubmed/28293270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12981-017-0140-4
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