Implication of overexpression of dishevelled-associated activator of morphogenesis 1 (Daam-1) for the pathogenesis of human Idiopathic Pulmonary Arterial Hypertension (IPAH)

BACKGROUND: Idiopathic pulmonary arterial hypertension (IPAH) is a rare, fatal disease of unknown pathogenesis. Evidence from our recent study suggests that IPAH pathogenesis is related to upregulation of the Wnt/planar cell polarity (Wnt/PCP) pathway. We used microscopic observation and immunohisto...

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Dades bibliogràfiques
Publicat a:Diagn Pathol
Autors principals: Yanai, Shun, Wakayama, Megumi, Nakayama, Haruo, Shinozaki, Minoru, Tsukuma, Hisayuki, Tochigi, Naobumi, Nemoto, Tetsuo, Saji, Tsutomu, Shibuya, Kazutoshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348773/
https://ncbi.nlm.nih.gov/pubmed/28288669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-017-0614-7
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