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Role and mechanism of action of leucine-rich repeat kinase 1 in bone
Leucine-rich repeat kinase 1 (LRRK1) plays a critical role in regulating cytoskeletal organization, osteoclast activity, and bone resorption with little effect on bone formation parameters. Deficiency of Lrrk1 in mice causes a severe osteopetrosis in the metaphysis of the long bones and vertebrae bo...
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| Yayımlandı: | Bone Res |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348726/ https://ncbi.nlm.nih.gov/pubmed/28326224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2017.3 |
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