Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica

Pathogenic autoantibodies associated with neuromyelitis optica (NMO) induce disease by targeting aquaporin-4 (AQP4) water channels enriched on astrocytic endfeet at blood–brain interfaces. AQP4 is also expressed at cerebrospinal fluid (CSF)–brain interfaces, such as the pial glia limitans and the ep...

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Publicat a:Acta Neuropathol
Autors principals: Guo, Yong, Weigand, Stephen D., Popescu, Bogdan F., Lennon, Vanda A., Parisi, Joseph E., Pittock, Sean J., Parks, Natalie E., Clardy, Stacey L., Howe, Charles L., Lucchinetti, Claudia F.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2017
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348570/
https://ncbi.nlm.nih.gov/pubmed/28184993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-017-1682-1
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