Immunoscore encompassing CD3+ and CD8+ T cell densities in distant metastasis is a robust prognostic marker for advanced colorectal cancer

BACKGROUND: The immunoscore (IS), an index based on the density of CD3(+) and CD8(+) tumor-infiltrating lymphocytes (TILs) in the tumor center (CT) and invasive margin (IM), has gained considerable attention as a prognostic marker. Tumor-associated macrophages (TAMs) have also been reported to have...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Kwak, Yoonjin, Koh, Jiwon, Kim, Duck-Woo, Kang, Sung-Bum, Kim, Woo Ho, Lee, Hye Seung
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348429/
https://ncbi.nlm.nih.gov/pubmed/27835889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13207
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