Integrated bioinformatics analysis of chromatin regulator EZH2 in regulating mRNA and lncRNA expression by ChIP sequencing and RNA sequencing

Enhancer of zeste homolog 2 (EZH2), a dynamic chromatin regulator in cancer, represents a potential therapeutic target showing early signs of promise in clinical trials. EZH2 ChIP sequencing data in 19 cell lines and RNA sequencing data in ten cancer types were downloaded from GEO and TCGA, respecti...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Li, Yuan, Luo, Mei, Shi, Xuejiao, Lu, Zhiliang, Sun, Shouguo, Huang, Jianbing, Chen, Zhaoli, He, Jie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348424/
https://ncbi.nlm.nih.gov/pubmed/27835578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13169
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