Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma

ADP-ribosylation factor (ARF)-like 4c (ARL4C) expression, induced by a combination of Wnt/β-catenin and EGF/Ras signaling, has been demonstrated to form epithelial morphogenesis. ARL4C overexpression, due to Wnt/β-catenin and EGF/Ras signaling alterations, was involved in tumorigenesis. It was also...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fujii, Shinsuke, Shinjo, Keiko, Matsumoto, Shinji, Harada, Takeshi, Nojima, Satoshi, Sato, Sunao, Usami, Yu, Toyosawa, Satoru, Morii, Eiichi, Kondo, Yutaka, Kikuchi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348413/
https://ncbi.nlm.nih.gov/pubmed/27835592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13147
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