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Anti-EGFR antibody sensitizes colorectal cancer stem-like cells to Fluorouracil-induced apoptosis by affecting autophagy

Recent reports suggest that colorectal carcinoma (CRC) may be sustained by a small subpopulation of cells, termed cancer stem cells (CSCs), which have drug resistance properties as a key reason for chemotherapy failure. The epidermal growth factor receptor (EGFR) controls CRC initiation and progress...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Feng, Ye, Gao, Shuohui, Gao, Yongjian, Wang, Xuefeng, Chen, Zhi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348401/
https://ncbi.nlm.nih.gov/pubmed/27833077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13233
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