p16 overexpression and 9p21 deletion are linked to unfavorable tumor phenotype in breast cancer

Overexpression of the p16 tumor suppressor, but also deletion of its gene locus 9p21, is linked to unfavorable tumor phenotype and poor prognosis in breast cancer. To better understand these contradictory observations, and to clarify the prognostic impact of p16 expression and 9p21 deletion, a tissu...

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Vydáno v:Oncotarget
Hlavní autoři: Lebok, Patrick, Roming, Magdalena, Kluth, Martina, Koop, Christina, Özden, Cansu, Taskin, Berivan, Hussein, Khakan, Lebeau, Annette, Witzel, Isabell, Wölber, Linn, Geist, Stefan, Paluchowski, Peter, Wilke, Christian, Heilenkötter, Uwe, Müller, Volkmar, Schmalfeldt, Barbara, Simon, Ronald, Sauter, Guido, Terracciano, Luigi, Krech, Rainer Horst, von der Assen, Albert, Burandt, Eike
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348395/
https://ncbi.nlm.nih.gov/pubmed/27835607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13227
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