Lung tissue remodelling in MCT-induced pulmonary hypertension: a proposal for a novel scoring system and changes in extracellular matrix and fibrosis associated gene expression

Pulmonary hypertension (PH) is associated with vasoconstriction and remodelling. We studied lung tissue remodelling in a rat model of PH with special focus on histology and extracellular matrix (ECM) remodelling. After induction of PH by monocrotaline, lung tissue was analysed histologically, by gen...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Franz, Marcus, Grün, Katja, Betge, Stefan, Rohm, Ilonka, Ndongson-Dongmo, Bernadin, Bauer, Reinhard, Schulze, P. Christian, Lichtenauer, Michael, Petersen, Iver, Neri, Dario, Berndt, Alexander, Jung, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348389/
https://ncbi.nlm.nih.gov/pubmed/27835899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13220
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