Oncolytic vaccinia virus combined with radiotherapy induces apoptotic cell death in sarcoma cells by down-regulating the inhibitors of apoptosis

Advanced extremity melanoma and sarcoma present a significant therapeutic challenge, requiring multimodality therapy to treat or even palliate disease. These aggressive tumours are relatively chemo-resistant, therefore new treatment approaches are urgently required. We have previously reported on th...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wilkinson, Michelle J., Smith, Henry G., McEntee, Gráinne, Kyula-Currie, Joan, Pencavel, Tim D., Mansfield, David C., Khan, Aadil A., Roulstone, Victoria, Hayes, Andrew J., Harrington, Kevin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348387/
https://ncbi.nlm.nih.gov/pubmed/27783991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12820
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