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Metformin enhances the radiosensitivity of human liver cancer cells to γ–rays and carbon ion beams

The purpose of this study was to investigate the effect of metformin on the responses of hepatocellular carcinoma (HCC) cells to γ–rays (low-linear energy transfer (LET) radiation) and carbon-ion beams (high-LET radiation). HCC cells were pretreated with metformin and exposed to a single dose of γ–r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kim, Eun Ho, Kim, Mi-Sook, Furusawa, Yoshiya, Uzawa, Akiko, Han, Soorim, Jung, Won-Gyun, Sai, Sei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348341/
https://ncbi.nlm.nih.gov/pubmed/27802188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12966
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