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Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin (PTN) augments tumor growth by increasing proliferation of tumor cells and promoting vascular abnormalization, but its role in early gliomagenesis has not been evaluated. Through analysis of publically available datasets, we demonstrate that increased PTN mRNA expression is associated w...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Zhang, Lei, Laaniste, Liisi, Jiang, Yiwen, Alafuzoff, Irina, Uhrbom, Lene, Dimberg, Anna
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348327/
https://ncbi.nlm.nih.gov/pubmed/27806344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12983
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