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Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin (PTN) augments tumor growth by increasing proliferation of tumor cells and promoting vascular abnormalization, but its role in early gliomagenesis has not been evaluated. Through analysis of publically available datasets, we demonstrate that increased PTN mRNA expression is associated w...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Lei, Laaniste, Liisi, Jiang, Yiwen, Alafuzoff, Irina, Uhrbom, Lene, Dimberg, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348327/
https://ncbi.nlm.nih.gov/pubmed/27806344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12983
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