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Pleiotrophin enhances PDGFB-induced gliomagenesis through increased proliferation of neural progenitor cells

Pleiotrophin (PTN) augments tumor growth by increasing proliferation of tumor cells and promoting vascular abnormalization, but its role in early gliomagenesis has not been evaluated. Through analysis of publically available datasets, we demonstrate that increased PTN mRNA expression is associated w...

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發表在:Oncotarget
Main Authors: Zhang, Lei, Laaniste, Liisi, Jiang, Yiwen, Alafuzoff, Irina, Uhrbom, Lene, Dimberg, Anna
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348327/
https://ncbi.nlm.nih.gov/pubmed/27806344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12983
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