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Smad4 in T cells plays a protective role in the development of autoimmune Sjögren's syndrome in the nonobese diabetic mouse
We investigated the role of Smad4, a signaling molecule of the TGF-beta pathway, in T cells on the pathology of Sjögren's syndrome (SS) in nonobese diabetic (NOD) mice, an animal model of SS. T cell-specific Smad4-deleted (Smad4(fl/fl,CD4-Cre); Smad4 tKO) NOD mice had accelerated development of...
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| Publicado no: | Oncotarget |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5348321/ https://ncbi.nlm.nih.gov/pubmed/27880731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13437 |
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