Elevated BMI and Antibodies to Citrullinated Proteins Interact to Increase Rheumatoid Arthritis Risk and Shorten Time to Diagnosis: a Nested Case-Control Study of Women in the Nurses’ Health Studies

OBJECTIVE: Overweight/obesity and anti-citrullinated protein antibodies (ACPA) increase RA risk. We investigated the relationship between body mass index (BMI) and ACPA, tested for an interaction between BMI and ACPA for RA risk, and examined effects of BMI and ACPA on time to RA diagnosis. DESIGN:...

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Publicado no:Semin Arthritis Rheum
Main Authors: Tedeschi, Sara K., Cui, Jing, Arkema, Elizabeth V., Robinson, William H., Sokolove, Jeremy, Lingampalli, Nithya, Sparks, Jeffrey A., Karlson, Elizabeth W., Costenbader, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348285/
https://ncbi.nlm.nih.gov/pubmed/27939764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semarthrit.2016.09.001
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