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Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice

Serotonin (5-HT) and brain derived neurotrophic factor (BDNF) are two signaling molecules that play important regulatory roles in the development and plasticity of neural circuits that are known to be altered in depression. However, the mechanism by which 5-HT regulates BDNF signaling is unknown. In...

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Foilsithe in:Mol Psychiatry
Main Authors: Pandya, Chirayu D, Hoda, Nasrul, Crider, Amanda, Peter, Diya, Kutiyanawalla, Ammar, Kumar, Sanjiv, Ahmed, Anthony O, Turecki, Gustavo, Hernandez, Caterina M, Terry, Alvin V, Pillai, Anilkumar
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348279/
https://ncbi.nlm.nih.gov/pubmed/27620841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.145
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