Early evidence of multiple sclerosis in a prospective study of high-risk family members

IMPORTANCE: Subclinical inflammatory demyelination and neurodegeneration likely precede symptom onset in multiple sclerosis (MS). OBJECTIVE: To investigate the prevalence of brain magnetic resonance imaging (MRI) and subclinical abnormalities in asymptomatic individuals at risk for MS. DESIGN, SETTI...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Xia, Zongqi, Steele, Sonya U., Bakshi, Anshika, Clarkson, Sarah R., White, Charles C., Schindler, Matthew K., Dewey, Blake E., Ohayon, Joan, Chibnik, Lori B., Cortese, Irene C. M., De Jager, Philip L., Reich, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348267/
https://ncbi.nlm.nih.gov/pubmed/28114441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.5056
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