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Trauma-induced acute X chromosome skewing in white blood cells represents an immuno-modulatory mechanism unique to females and a likely contributor to sex-based outcome differences

Sex-related outcome disparities following severe trauma have been demonstrated in human and animal studies however sex hormone status could not fully account for the differences. This study tested whether X-linked cellular mosaicism, which is unique to females, could represent a genetically based me...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Pena, Geber, Michalski, Christina, Qin, Yong, Donnelly, Robert, Sifri, Ziad, Mosenthal, Anne, Livingston, David, Spolarics, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348261/
https://ncbi.nlm.nih.gov/pubmed/27749765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000764
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