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Disentangling the impact of within-host evolution and transmission dynamics on the tempo of HIV-1 evolution

BACKGROUND: Although evidence exists for a selective component at transmission, it is clear that HIV-1 transmission is also to a large extent driven by drift. The variation in inoculum size among different risk groups therefore implies that the adaptation rate of HIV may vary between epidemics with...

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Détails bibliographiques
Publié dans:AIDS
Auteurs principaux: Vrancken, Bram, Baele, Guy, Vandamme, Anne-Mieke, Van Laethem, Kristel, Suchard, Marc A., Lemey, Philippe
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348249/
https://ncbi.nlm.nih.gov/pubmed/26244394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000731
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