High levels of virological failure with major genotypic resistance mutations in HIV-1-infected children after 5 years of care according to WHO-recommended 1st-line and 2nd-line antiretroviral regimens in the Central African Republic: A cross-sectional study

A large cohort of 220 HIV-1-infected children (median [range] age: 12 [4–17] years) was cared and followed up in the Central African Republic, including 198 in 1st-line and 22 in 2nd-line antiretroviral regimens. Patients were monitored clinically and biologically for HIV-1 RNA load and drug resista...

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Bibliographic Details
Published in:Medicine (Baltimore)
Main Authors: Mossoro-Kpinde, Christian Diamant, Gody, Jean-Chrysostome, Mboumba Bouassa, Ralph-Sydney, Mbitikon, Olivia, Jenabian, Mohammad-Ali, Robin, Leman, Matta, Mathieu, Zeitouni, Kamal, Longo, Jean De Dieu, Costiniuk, Cecilia, Grésenguet, Gérard, Touré Kane, Ndèye Coumba, Bélec, Laurent
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Health 2017
Subjects:
4850
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348195/
https://ncbi.nlm.nih.gov/pubmed/28272247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000006282
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