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Induction of acetylcholine receptor alpha-subunit gene expression in chicken myotubes by blocking electrical activity requires ongoing protein synthesis.

The level of acetylcholine receptor alpha-subunit mRNA in primary cultures of chicken myotubes increases when the spontaneous electrical activity of the myotube is suppressed by the sodium channel blocker tetrodotoxin. This increase was prevented by two translational inhibitors: cycloheximide and an...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Duclert, A, Piette, J, Changeux, J P
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1990
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1391
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