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N-Hydroxyimide Ugi Reaction toward α-Hydrazino Amides

[Image: see text] The Ugi four-component reaction (U-4CR) with N-hydroxyimides as a novel carboxylic acid isostere has been reported. This reaction provides straightforward access to α-hydrazino amides. A broad range of aldehydes, amines, isocyanides and N-hydroxyimides were employed to give product...

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Publicat a:Org Lett
Autors principals: Chandgude, Ajay L., Dömling, Alexander
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5348098/
https://ncbi.nlm.nih.gov/pubmed/28220702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b00205
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