CP-31398, a putative p53-stabilizing molecule tested in mammalian cells and in yeast for its effects on p53 transcriptional activity

BACKGROUND: CP-31398 is a small molecule that has been reported to stabilize the DNA-binding core domain of the human tumor suppressor protein p53 in vitro. The compound was also reported to function as a potential anti-cancer drug by rescuing the DNA-binding activity and, consequently, the transcri...

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I whakaputaina i:	J Negat Results Biomed
Ngā kaituhi matua:	Tanner, Stefan, Barberis, Alcide
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2004
Ngā marau:	Research
Urunga tuihono:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534789/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15548325/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1477-5751-3-5
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