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Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma

Neuroblastoma is the most common human extracranial solid tumor during infancy. Involvement of several miRNAs in its pathogenesis has been ascertained. Interestingly, most of their encoding genes reside in hypermethylated genomic regions: thus, their tumor suppressor function is normally disallowed...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Maugeri, Marco, Barbagallo, Davide, Barbagallo, Cristina, Banelli, Barbara, Di Mauro, Stefania, Purrello, Francesco, Magro, Gaetano, Ragusa, Marco, Di Pietro, Cinzia, Romani, Massimo, Purrello, Michele
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347773/
https://ncbi.nlm.nih.gov/pubmed/27829219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13090
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