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Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia
The relative contribution of resident microglia and peripheral monocyte-derived macrophages in neuroinflammation after cranial irradiation is not known. A single dose of 8 Gy was administered to postnatal day 10 (juvenile) or 90 (adult) CX3CR1(GFP/+) CCR2(RFP/+) mouse brains. Microglia accumulated i...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Oncotarget |
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Κύριοι συγγραφείς: | , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Impact Journals LLC
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347693/ https://ncbi.nlm.nih.gov/pubmed/27793054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12929 |
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