Observations of reaction intermediates and the mechanism of aldose-ketose interconversion by D-xylose isomerase.
Crystallographic studies of D-xylose isomerase (D-xylose ketol-isomerase, EC 5.3.1.5) incubated to equilibrium with substrate/product mixtures of xylose and xylulose show electron density for a bound intermediate. The accumulation of this bound intermediate shows that the mechanism is a non-Michaeli...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53475/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2304904/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.4.1362 |
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