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The Strange Case of CDK4/6 Inhibitors: Mechanisms, Resistance, and Combination Strategies
CDK4/6 inhibitors have emerged as a powerful class of agents with clinical activity in a number of malignancies. Targeting the cell cycle represents a core attack on a defining feature of cancer. However, the mechanisms through which selective CDK4/6 targeted agents act has few parallels in the curr...
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| Publicado en: | Trends Cancer |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347397/ https://ncbi.nlm.nih.gov/pubmed/28303264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.11.006 |
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