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A codon-shuffling method to prevent reversion during production of replication-defective herpesvirus stocks: Implications for herpesvirus vaccines

Herpesviruses establish life-long chronic infections that place infected hosts at risk for severe disease. Herpesvirus genomes readily undergo homologous recombination (HR) during productive replication, often leading to wild-type (WT) reversion during complementation of replication-defective and at...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Li, Gang, Ward, Charles, Yeasmin, Rukhsana, Skiena, Steven, Krug, Laurie T., Forrest, J. Craig
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347388/
https://ncbi.nlm.nih.gov/pubmed/28287622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44404
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