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Elevated Cholesterol in the Coxiella burnetii Intracellular Niche Is Bacteriolytic

Coxiella burnetii is an intracellular bacterial pathogen and a significant cause of culture-negative endocarditis in the United States. Upon infection, the nascent Coxiella phagosome fuses with the host endocytic pathway to form a large lysosome-like vacuole called the parasitophorous vacuole (PV)....

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Publicat a:mBio
Autors principals: Mulye, Minal, Samanta, Dhritiman, Winfree, Seth, Heinzen, Robert A., Gilk, Stacey D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347348/
https://ncbi.nlm.nih.gov/pubmed/28246364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02313-16
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