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Defective lysosomal exocytosis and plasma membrane repair in Chediak–Higashi/beige cells

Plasma membrane resealing is a Ca(2+)-dependent process that involves the exocytosis of intracellular vesicles next to the wound site. Recent studies revealed that conventional lysosomes behave as Ca(2+)-regulated secretory compartments and play a central role in membrane resealing. These findings r...

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Detalhes bibliográficos
Main Authors: Huynh, Chau, Roth, Doris, Ward, Diane M., Kaplan, Jerry, Andrews, Norma W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534728/
https://ncbi.nlm.nih.gov/pubmed/15557559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405905101
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