NLRX1 accelerates cisplatin-induced ototoxity in HEI-OC1 cells via promoting generation of ROS and activation of JNK signaling pathway

Nucleotide-binding domain and leucine-rich-repeat-containing family member X1 (NLRX1), located in mitochondria, can recognize cytoplasmic pattern recognition receptors and is tightly related to reactive oxygen species (ROS) production, mitochondrial function, apoptosis and inflammation. The present...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Yin, Haiyan, Sun, Gaoying, Yang, Qianqian, Chen, Chen, Qi, Qi, Wang, Haibo, Li, Jianfeng
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347132/
https://ncbi.nlm.nih.gov/pubmed/28287190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44311
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki