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Neurovascular microcirculatory vasodilation mediated by C-fibers and Transient receptor potential vanilloid-type-1 channels (TRPV 1) is impaired in type 1 diabetes

Microvascular dysfunction may have an early onset in type 1 diabetes (T1D) and can precede major complications. Our objectives were to assess the endothelial-dependent (acetylcholine, ACh; and post-occlusive hyperemia, PORH), non-endothelial-dependent (sodium nitroprusside, SNP) and neurovascular-de...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Marche, P., Dubois, S., Abraham, P., Parot-Schinkel, E., Gascoin, L., Humeau-Heurtier, A., Ducluzeau, PH., Mahe, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347083/
https://ncbi.nlm.nih.gov/pubmed/28287157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44322
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