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A new solvate of afatinib, a specific inhibitor of the ErbB family of tyrosine kinases
Afatinib (systematic name: N-{4-(3-chloro-4-fluoroanilino)-7-[(tetrahydrofuran-3-yl)oxy]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide), is a specific inhibitor of the ErbB family of tyrosine kinases. The free base form crystallizes from acetonitrile as a mixed water–acetonitrile solvent,...
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| Publicado no: | Acta Crystallogr E Crystallogr Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5347068/ https://ncbi.nlm.nih.gov/pubmed/28316823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2056989017002626 |
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