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Novel enhancement mechanism of tyrosine hydroxylase enzymatic activity by nitric oxide through S-nitrosylation

Tyrosine hydroxylase (TH) is a rate-limiting step enzyme in the synthesis of catecholamines. Catecholamines function both as hormone and neurotransmitters in the peripheral and central nervous systems, therefore TH’s expression and enzymatic activity is tightly regulated by various mechanisms. Sever...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Yuanyuan, Sung, Chun Chau, Chung, Kenny K. K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5347018/
https://ncbi.nlm.nih.gov/pubmed/28287127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44154
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