Glypican-5 suppresses Epithelial-Mesenchymal Transition of the lung adenocarcinoma by competitively binding to Wnt3a

We previously demonstrated that Glypican-5 (GPC5), one of the members of heparan sulfate proteoglycan, was a novel tumor metastasis suppressor in lung adenocarcinoma (LAC). However, it remains unclear how GPC5 suppresses lung cancer metastasis. Here, we found over-expression GPC5 induced significant...

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Опубликовано в: :Oncotarget
Главные авторы: Wang, Siwei, Qiu, Mantang, Xia, Wenjia, Xu, Youtao, Mao, Qixing, Wang, Jie, Dong, Gaochao, Xu, Lin, Yang, Xin, Yin, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346747/
https://ncbi.nlm.nih.gov/pubmed/27806326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12945
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