Epigallocatechin-3-gallate(EGCG) suppresses melanoma cell growth and metastasis by targeting TRAF6 activity

TRAF6 (TNF Receptor-Associated Factor 6) is an E3 ubiquitin ligase that contains a Ring domain, induces K63-linked polyubiquitination, and plays a critical role in signaling transduction. Our previous results demonstrated that TRAF6 is overexpressed in melanoma and that TRAF6 knockdown dramatically...

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Vydáno v:Oncotarget
Hlavní autoři: Zhang, Jianglin, Lei, Zhou, Huang, Zunnan, Zhang, Xu, Zhou, Youyou, Luo, Zhongling, Zeng, Weiqi, Su, Juan, Peng, Cong, Chen, Xiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346735/
https://ncbi.nlm.nih.gov/pubmed/27791197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12836
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