A combined gene expression and functional study reveals the crosstalk between N-Myc and differentiation-inducing microRNAs in neuroblastoma cells

MYCN amplification is the most common genetic alteration in neuroblastoma and plays a critical role in neuroblastoma tumorigenesis. MYCN regulates neuroblastoma cell differentiation, which is one of the mechanisms underlying its oncogenic function. We recently identified a group of differentiation-i...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Zhao, Zhenze, Ma, Xiuye, Shelton, Spencer D., Sung, Derek C., Li, Monica, Hernandez, Daniel, Zhang, Maggie, Losiewicz, Michael D., Chen, Yidong, Pertsemlidis, Alexander, Yu, Xiaojie, Liu, Yuanhang, Du, Liqin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346721/
https://ncbi.nlm.nih.gov/pubmed/27764804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12676
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