A randomized phase II trial comparing chemoimmunotherapy with or without bevacizumab in previously untreated patients with chronic lymphocytic leukemia

Bevacizumab is a monoclonal antibody targeting vascular endothelial growth factor (VEGF) with in vitro pro-apoptotic and antiangiogenic effects on chronic lymphocytic leukemia (CLL) cells. As monotherapy in patients with CLL, it has no clinical activity. Here we report the results of an open-label,...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Kay, Neil E., Strati, Paolo, LaPlant, Betsy R., Leis, Jose F., Nikcevich, Daniel, Call, Timothy G., Pettinger, Adam M., Lesnick, Connie E., Hanson, Curtis A., Shanafelt, Tait D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
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Priority Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346637/
https://ncbi.nlm.nih.gov/pubmed/27861157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13412
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