CPI-17 drives oncogenic Ras signaling in human melanomas via Ezrin-Radixin-Moesin family proteins

Hyperactive Ras signaling has strong oncogenic effects causing several different forms of cancer. Hyperactivity is frequently induced by mutations within Ras itself, which account for up to 30% of all human cancers. In addition, hyperactive Ras signaling can also be triggered independent of Ras by e...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Riecken, Lars Björn, Zoch, Ansgar, Wiehl, Ulrike, Reichert, Sabine, Scholl, Ingmar, Cui, Yan, Ziemer, Mirjana, Anderegg, Ulf, Hagel, Christian, Morrison, Helen
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Priority Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346635/
https://ncbi.nlm.nih.gov/pubmed/27793041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12919
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