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The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila

Diverse extrinsic and intrinsic cues must be integrated within a developing organism to ensure appropriate growth at the cellular and organismal level. In Drosophila, the insulin receptor/TOR/S6K signaling network plays a fundamental role in the control of metabolism and cell growth. Here we show th...

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Detalhes bibliográficos
Main Authors: Reiling, Jan H., Hafen, Ernst
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534649/
https://ncbi.nlm.nih.gov/pubmed/15545626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.322704
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