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Effects of FMO3 Polymorphisms on Pharmacokinetics of Sulindac in Chinese Healthy Male Volunteers

Sulindac is a nonsteroidal anti-inflammatory drug, which is clinically used for the ailments of various inflammations. This study investigated the allele frequencies of FMO3 E158K and E308G and evaluated the influences of these two genetic polymorphisms on the pharmacokinetics of sulindac and its me...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Tang, Yong-Jun, Hu, Kai, Huang, Wei-Hua, Wang, Chong-Zhi, Liu, Zhi, Chen, Yao, Ouyang, Dong-Sheng, Tan, Zhi-Rong, Zhou, Hong-Hao, Yuan, Chun-Su
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346382/
https://ncbi.nlm.nih.gov/pubmed/28331852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4189678
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