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The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA

The identification of permissible HLA class II mismatches can prevent DSA in mismatched transplantation. The HLA-DR phenotype of recipients contributes to DSA formation by presenting allo-HLA-derived peptides to T-helper cells, which induces the differentiation of B cells into plasma cells. Comparin...

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Vydáno v:J Immunol Res
Hlavní autor: Jucaud, Vadim
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346368/
https://ncbi.nlm.nih.gov/pubmed/28331856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2748614
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