Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue

BACKGROUND: Poor bone quality, increased fracture risks, and impaired bone healing are orthopedic comorbidities of type 1 diabetes (T1DM). Standard osteogenic growth factor treatments are inadequate in fully rescuing retarded healing of traumatic T1DM long bone injuries where both periosteal and bon...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Filion, Tera M., Skelly, Jordan D., Huang, Henry, Greiner, Dale L., Ayers, David C., Song, Jie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346267/
https://ncbi.nlm.nih.gov/pubmed/28283030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-017-0521-6
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