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Age-related macular degeneration phenotypes are associated with increased tumor necrosis-alpha and subretinal immune cells in aged Cxcr5 knockout mice

The role of chemokine receptor in age-related macular degeneration (AMD) remains elusive. The objective of this study is to investigate the role of chemokine receptor Cxcr5 in the pathogenesis of AMD. Cxcr5 gene expression levels (mRNA and protein) are higher in the retina and retinal pigment epithe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Hu, Liu, Ying, Wang, Lei, Li, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345864/
https://ncbi.nlm.nih.gov/pubmed/28282423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173716
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