Administration of tranexamic acid to patients undergoing surgery for adolescent idiopathic scoliosis evokes pain and increases the infusion rate of remifentanil during the surgery

BACKGROUND: We recently reported that tranexamic acid (TXA) evokes pain in rats by inhibiting γ-aminobutyric acid and glycine receptors on neurons in the spinal dorsal horn. Although TXA is commonly used to reduce perioperative blood loss during various surgeries, its potential to induce intraoperat...

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Udgivet i:PLoS One
Main Authors: Ohashi, Nobuko, Ohashi, Masayuki, Endo, Naoto, Kohno, Tatsuro
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345863/
https://ncbi.nlm.nih.gov/pubmed/28282425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173622
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