The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia: Haas et al: PCSK9 in Nephrotic Syndrome Hypercholesterolemia

BACKGROUND: In nephrotic syndrome, damage to the podocytes of the kidney produces severe hypercholesterolemia for which novel treatments are urgently needed. Proprotein convertase subtilisin/kexin type 9 (PCSK9) has emerged as an important regulator of plasma cholesterol levels and therapeutic targe...

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Veröffentlicht in:Circulation
Hauptverfasser: Haas, Mary E., Levenson, Amy E., Sun, Xiaowei, Liao, Wan-Hui, Rutkowski, Joseph M., de Ferranti, Sarah D, Schumacher, Valerie A., Scherer, Philipp E., Salant, David J., Biddinger, Sudha B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345853/
https://ncbi.nlm.nih.gov/pubmed/27358438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.020912
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